GenoRxiv – Mapping scientific literature on the genome

Hacker News

Ever get lost searching through genetic literature? I've built a new interface for bioRxiv+medRxiv to directly browse preprint findings on the genome! To begin I downloaded 7TB's of bioRxiv+medRxiv preprints and extracted mentions of genetic variant ID's or positions. Documented in "How to download bioRxiv on a budget": http://sitlabs.org/writing/biorxiv.html This project started after I was trawling through Google Scholar to review a gene when I realised I had missed relevant upstream findings which hadn't been linked to the gene. I wondered if there could be a better interface to explore genetic literature? Next I provided the variant mentions and paper context to gpt-4o-mini and requested structured output summarising the scientific finding. Finally I mapped all variants to the latest genome build and plotted them on our custom genome browser. This project was made by the new Scientific Interface & Tooling Lab ( http://sitlabs.org ) at Oxford. We will be releasing new interfaces and tools to improve scientific productivity with an initial focus on biology research.

Visit product View on Hacker NewsDec 18, 2024

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